Water-Reprocessable, Reformable, and Ecofriendly Sustainable Material Based on Disulfide-Cross-Linked Polyethyleneimine

Swelling Kinetics of Disulfide Cross-Linked Microgels

Hydrogels of 2-hydroxyethyl methacrylate (HEMA) cross-linked with N,N′-cystaminebis(acrylamide) (CBA) were prepared inside microchannels using an in situ photopolymerization for the study of chemical-responsive microgels. By chemically reducing disulfide bonds with dithiothreitol (DTT), the cross-link density of the hydrogel network decreased, leading to an observable swelling of the hydrogel. ...

New type of membrane material for water desalination based on a cross-linked bicontinuous cubic lyotropic liquid crystal assembly.

Improved antigen cross-presentation by polyethyleneimine-based nanoparticles

PURPOSE In the development of therapeutic vaccines against cancer, it is important to design strategies for antigen cross-presentation to stimulate cell-mediated immune responses against tumor antigens. METHODS We developed a polyethyleneimine (PEI)-based protein antigen delivery system to promote cross-presentation through the major histocompatibility complex (MHC) I pathway using ovalbumin ...

“On-Water” Catalyst-Free Ecofriendly Synthesis of the Hantzsch Dihydropyridines

An eco-friendly "on-water" protocol for efficient catalyst-free synthesis of the Hantzsch dihydropyridines from aryl, heteroaryl, alkyl, and vinylogous aldehydes has been developed with minimum auxiliary substances, toxic reagents, organic solvents, and disposal problems.

Disulfide-linked protein folding pathways.

Determining the mechanism by which proteins attain their native structure is an important but difficult problem in basic biology. The study of protein folding is difficult because it involves the identification and characterization of folding intermediates that are only very transiently present. Disulfide bond formation is thermodynamically linked to protein folding. The availability of thiol t...